Service Information: Service for Analyzing Collagen Type II Quantitative in Various Products
VISBIO Co., Ltd provides a service for the examination and quantitative analysis of Collagen Type II in various health and beauty industry or food and beverage industry or raw materials component of collagen II.
The human body consists of multiple types of collagens, each with different functions and locations within the body. Collagen Type II is one of these proteins and is predominantly found in the flexible and sturdy tissues of developing joints, particularly in the cartilage. It is also present in bones and various other connective tissues throughout the body.
Collagen Type II assists in increasing the level of hyaluronic acid, an essential component of joint fluid, and inhibits enzymes that degrade this fluid. This ability can aid in reducing joint pain and stiffness, thereby enhancing overall body movement. Given its popularity in the health and beauty industry, Collagen Type II is commonly used as an ingredient in dietary supplements known for nourishing knee joints. Consequently, analyzing the quantity of Collagen Type II is considered a crucial quality control measure that bolsters trust in your products.
Collagen Type II: What Is It?
The human body consists of various types of collagen, each with distinct functions and locations within the body. In this article, we will explain the origin, mechanism of action, and significance of Collagen Type II.
Collagen Type II is one of the proteins predominantly found in the cartilage of developing joints. Cartilage is a flexible and robust connective tissue mainly located in joint areas.
Most of the cartilage in the human body eventually transforms into bone, except for the cartilage covering the ends of certain bones, such as the nose or ears. Collagen Type II is the only collagen type present in the cartilage of developing joints, distinguishing it from other collagen types primarily found in the skin cells, including Collagen Types 1, 3, and 4.
Collagen Type II plays a crucial role in repairing damaged joint components by stimulating the synthesis of growth cells. It enhances the production of Hyaluronic acid, a key component of joint synovial fluid, and inhibits the activity of enzymes responsible for breaking down joint lubricants. These properties contribute to alleviating joint pain and stiffness, ultimately improving mobility.
Moreover, Collagen Type II is a significant component of the clear gel that fills the vitreous chamber of the eye (vitreous humor). It consists of dry weight and Collagen. Collagen Type II has many benefits for cells that promote and stimulate the production of growth cells synthesized from Hyaluronic acid and increased protein. This helps reduce the level of inflammatory joint circulation. The nature of Collagen Type II is typically pale yellow.
Sources and Benefits of Collagen Type II
Normally, the human body can produce Collagen Type II on its own. However, as people age, the production process tends to decrease. Therefore, for elderly individuals experiencing joint pain or knee problems, consuming foods with Collagen Type II can be beneficial.
Collagen Type II can be found in various foods, including animal meats, certain vegetables and fruits, deep-sea fish like salmon and tuna, seaweed, and some types of mushrooms. Green leafy vegetables like spinach or broccoli also contain Collagen Type II. Additionally, it is abundant in the bone of animals, especially chicken. This type of collagen is known for its role in promoting flexible and strong joints. Consequently, Collagen Type II is particularly useful for joint health.
Collagen Type II, derived from chicken bone, has specific properties that are advantageous for joint health. It can help alleviate joint pain associated with various types of inflammatory joint conditions, enhancing joint resilience and flexibility. Furthermore, it acts as a lubricant, facilitating smooth joint movement without friction. Collagen Type II also strengthens the connective tissues that support muscles, organs and skin in the body.
Collagen Type II about Osteoarthritis or Rheumatoid Arthritis
The treatment of osteoarthritis involves various approaches, but some methods may have undesirable side effects. For instance, certain pain-relief medications can lead to stomach ulcers, and surgical interventions may require extended recovery periods. Researchers have been exploring alternative methods and new treatments for continuous osteoarthritis care.
One approach has been the investigation of natural products or dietary supplements to prevent and manage knee problems and osteoarthritis. These methods aim to strengthen the joints, increase joint lubrication, and provide safe options for those affected. Some popular dietary supplements that gained attention include glucosamine and chondroitin, as research suggested they could reduce pain in individuals with chronic joint inflammation. However, there is still limited definitive evidence regarding their benefits for osteoarthritis.
Currently, research studies are focusing on Undenatured Collagen Type II, extracted from chicken sternum cartilage. It has shown promise in reducing inflammation in patients with rheumatoid arthritis. Additionally, animal experiments involving overweight subjects with knee osteoarthritis found that collagen Type II supplementation (40 milligrams daily for 90 days) improved knee osteoarthritis symptoms. However, discontinuing collagen Type II supplementation led to a return of symptoms within 30 days.
Furthermore, studies have explored the anti-inflammatory properties of collagen Type II, finding that it can inhibit the destruction of cartilage cells by suppressing the activity of Regulatory T lymphocytes and controlling the levels of interleukin-10 and TGF-alpha. These mechanisms help reduce pain and inflammation in individuals with inflammatory joint diseases.
Testing and Analysis: Quantity of Collagen Type II
Collagen Type II used as an ingredient in dietary supplements or food and beverage industries and widely available in the market comes in the form of Denatured Collagen Type II or Hydrolyzed Collagen Type II. These forms have undergone processes to reduce their size and enhance absorption in the body. On the other hand, Undenatured Collagen Type II has a structure that closely resembles collagen in the cartilage of the knee joint. Currently, there are various methods for analyzing the specificity of Collagen Type II in products. These methods include the use of Mass spectrometry, which is a technique used to analyze the mass-to-charge ratio of charged particles, helping identify the mass and chemical composition of molecules such as peptides and other chemical components. Alternatively, testing can be conducted using the Human Collagen Type II (COL2) test kit.
Literature:
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- พญ. นงนภัส เก้าเอี้ยน, คอลลาเจนไทพ์ทู (Collagen Type II) ทางเลือกใหม่ไขปัญหาข้อเสื่อม, (ออนไลน์).สืบค้นจาก : https://www.pobpad.com/%E0%B8%84%E0%B8%AD%E0%B8%A5%E0%B8%A5%E0%B8%B2%E0%B9%80%E0%B8%88%E0%B8%99%E0%B9%84%E0%B8%97%E0%B8%9E%E0%B9%8C%E0%B8%97%E0%B8%B9-collagen-type-ii-%E0%B8%97%E0%B8%B2%E0%B8%87%E0%B9%80%E0%B8%A5%E0%B8%B7 วันที่สืบค้น 17082566
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