About Our High Blood Pressure Control Supplement Product Efficacy Testing Services
Maintaining good health is essential, and dietary supplements play a role in healthcare. Controlling high blood pressure is a primary goal for health-conscious consumers. Producing effective blood pressure-lowering supplements is a significant challenge for brand owners and manufacturers. To ensure consumers receive safe and effective products, cell-level product testing supplements is indispensable. This article details our blood pressure supplement efficacy testing services, focusing on ACE1 inhibition activity testing, anti-inflammatory activity testing, and cell toxicity testing.
High blood pressure, or hypertension, is a common health problem affecting many people worldwide. It’s a major risk factor for cardiovascular disease, stroke, and chronic kidney disease. Controlling blood pressure is crucial for preventing and reducing the risk of these diseases.
Meanwhile, the market for blood pressure-lowering supplements is growing steadily. Consumers are turning to natural products, such as herbal blood pressure reducers, that may complement treatment and prevent hypertension. However, the efficacy and safety of these products remain issues that require rigorous testing.
To meet consumer needs and ensure product quality, cell-level efficacy testing of blood pressure control supplements is a vital tool that helps manufacturers and brand owners scientifically validate product efficacy and safety.
High Blood Pressure: Causes and Effects
High blood pressure arises from various causes, including genetic factors and lifestyle behaviors like high sodium intake, lack of exercise, and stress. Additionally, certain medical conditions, such as diabetes and kidney disease, can increase the risk of hypertension.
The health effects of high blood pressure are severe and diverse. It’s a leading cause of cardiovascular diseases like coronary artery disease and acute myocardial infarction. It also increases the risk of stroke, paralysis, and chronic kidney failure.
The Role of Supplements in Blood Pressure Control
Supplements play a significant role in helping control blood pressure through various mechanisms, including balancing nutrients in the body, reducing inflammation, and improving blood vessel function. Many nutrients and natural extracts have been studied and found to have the potential to significantly lower blood pressure.
Substances and Herbal Extracts with Blood Pressure-Lowering Potential
- Potassium: Plays a role in maintaining fluid and electrolyte balance in the body, helping to lower blood pressure by increasing sodium excretion through urine. Potassium supplements may be beneficial for individuals with potassium deficiency or those not getting enough potassium from their diet.
- Magnesium: Helps relax blood vessels and reduce vascular resistance, resulting in lower blood pressure. Magnesium supplementation may be beneficial for individuals with magnesium deficiency or those seeking to control blood pressure.
Coenzyme Q10 (CoQ10): An antioxidant that helps protect cells from damage and contributes to energy production in cells. CoQ10 supplementation may improve heart and blood vessel function and lower blood pressure in some hypertensive patients.
- Garlic: Garlic extract (Allicin) has been studied for its effects on blood pressure in patients with uncontrolled hypertension. A 12-week study involving patients taking two capsules of fermented garlic extract daily (480 mg) found that their systolic blood pressure decreased by an average of 11.8 mmHg. Fermented garlic extract was also found to be safe and well-tolerated in patients of all dosages. This study suggests that fermented garlic extract can be an effective and safe adjunct to prescription medications in treating hypertension.
Ginkgo Biloba: Ginkgo biloba leaf extract has vasodilatory effects and improves blood circulation. Studies have found that ginkgo biloba extract affects the expression of multiple genes related to immune response and endothelial cell function. This information helps understand the biological mechanisms of ginkgo biloba extract on the cardiovascular system, potentially leading to new treatments for cardiovascular diseases.
The Importance of Efficacy Testing
- Cell-level efficacy testing is crucial for manufacturers and researchers for several reasons:
- Building Product Credibility: Neutral and reliable test results build consumer confidence and increase marketing opportunities.
- Developing Effective Products: Test results help manufacturers understand the mechanisms of action of their products and enable them to improve formulations for better efficacy.
- Supporting Research and Development: Data from cell-level testing is valuable for researchers studying and developing blood pressure control supplements in the future.
VISBIO Co., Ltd. offers testing services related to blood pressure control supplements:
ACE1 Inhibition Activity Testing
ACE1 (Angiotensin-Converting Enzyme 1) is an enzyme that plays a crucial role in blood pressure regulation by converting angiotensin I to angiotensin II, which causes blood vessels to constrict and blood pressure to rise. Inhibiting ACE1 activity can help lower blood pressure. Testing the ACE1 inhibitory activity of supplements is a vital step in confirming product efficacy. It uses biochemical methods and cell-level experiments to measure the ability of extracts in supplements to inhibit ACE1. Test results help manufacturers and brand owners ensure their products effectively lower blood pressure. [Click for more details on ACE1 inhibition activity testing (Anti-ACE1) affecting blood pressure]
Anti-Inflammatory Activity Testing by Nitric Oxide Assay
Inflammation contributes to high blood pressure. Anti-inflammatory activity testing using Nitric Oxide (NO) is a method to measure the effectiveness of herbal extracts or supplements in lowering high blood pressure. NO plays a role in vasodilation and reducing inflammation. This test assesses the product’s ability to increase NO levels in cells, indicating a reduction in inflammation. Test results help confirm that the product can lower blood pressure by reducing inflammation in the body. [Click for more details on Anti-Inflammatory Activity Testing by Nitric Oxide Assay]
Cell Toxicity Testing
This test evaluates the safety of dietary supplements at the cellular level, determining if the product is not toxic to cells. This is crucial for assessing product safety. Cell toxicity testing can be done using cell cultures in the laboratory to assess the effects of product ingredients on cells. [Click for more details on Cell Toxicity Testing of Products]
Contact Us for High Blood Pressure Control Supplement Efficacy Testing Services
VISBIO Co., Ltd. is committed to providing cell-level blood pressure control supplement testing services to meet the demands of today’s highly competitive market and increasing consumer expectations. We have developed a comprehensive testing package to ensure that products tested in our laboratory are certified for their true effectiveness. With a team of experts, our company is ready to be a trusted partner in developing and adding value to your products. With this experience and expertise, VISBIO Co., Ltd. aims to help manufacturers and brand owners build brands that are credible and trusted by consumers worldwide.
If you need further advice on cell-level blood pressure control supplement product testing services from our experts, please submit your product details for assessment or schedule a meeting with us to discuss suitable testing options for your product. You can reach us through our company’s contact channels [click here].
Literature:
- Aburto, N. J., Ziolkovska, A., Hooper, L., Elliott, P., Cappuccio, F. P., & Meerpohl, J. J. (2013). Effect of lower sodium intake on blood pressure: a systematic review and meta-analyses. BMJ, 346, f1326.
- Kass, L., Weekes, J., & Carpenter, L. (2012). Effect of magnesium supplementation on blood pressure: a meta-analysis. European Journal of Clinical Nutrition, 66(4), 411-418.
- Ried, K., Frank, O. R., & Stocks, N. P. (2019). Aged garlic extract reduces blood pressure in hypertensive individuals, mediating mechanotransduction signaling in vitro. Hypertension Research, 42(7), 1174-1184.
- Siepmann, M., & Kirch, W. (2002). Ginkgo biloba special extract EGb 761 in the treatment of mild cognitive impairment and Alzheimer’s disease: a review of efficacy and safety. Pharmacopsychiatry, 35(Suppl 1),S17-S26.
- Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., … & Watts, G. F. (2007). Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. Journal of Human Hypertension, 21(4), 297-306.