About Our Knee and Joint Supplement Product Testing Services

Caring for knee and joint health is crucial, especially for those with osteoarthritis or other knee problems. Joint health supplements like knee supplements, vitamins, and type II collagen have gained widespread popularity. The market for joint health supplements has been growing continuously, especially for products containing type II collagen, glucosamine, chondroitin, and hyaluronic acid, which are sought after by consumers looking to relieve osteoarthritis pain or strengthen their joints. However, competition in this market has also increased, making it necessary for manufacturers and brand owners to differentiate and establish credibility for their products. Product testing of supplements is key to raising product standards, increasing consumer confidence, and gaining a competitive advantage.

Trends in the Knee and Joint Health Supplement Market

  • Increasing Aging Population: The rise in the elderly population worldwide has led to a higher demand for joint health supplements, as older adults are more prone to osteoarthritis and other joint problems than other age groups.
  • Increased Health Awareness: People today are more health-conscious, leading them to seek out supplements to support joint health and prevent future knee problems.

Lifestyle Changes: Hectic lifestyles, sedentary jobs, and improper exercise habits all increase the risk of knee problems, prompting people to turn to supplements for joint care and maintenance.

Popular Ingredients in Knee and Joint Health Supplements

  • Collagen Type II: The main protein in cartilage, helping to strengthen and repair worn-out cartilage.
  • Glucosamine: A compound naturally found in cartilage, contributing to cartilage building and repair.
  • Chondroitin: Another compound found in cartilage, aiding in joint lubrication and reducing inflammation.
  • Hyaluronic Acid: A compound found in the fluid surrounding joints, helping to lubricate joints and reduce impact.
  • Other Natural Extracts: Such as turmeric, black sesame, ginseng, and others, known for their anti-inflammatory and joint-nourishing properties.

Knee and Joint Health Supplement Product Testing Services

To meet market demands and scientific advancements, knee and joint health supplement product testing services are crucial, especially comprehensive and standardized testing. This empowers manufacturers and brand owners to utilize the data for product development and build consumer trust.

VISBIO Co., Ltd. offers various testing services related to knee and joint health supplements:

Total Protein Quantification by TNBS Assay

This test measures the total protein content in joint health supplements. Protein plays a vital role in nourishing and repairing cartilage cells. The TNBS assay is a precise and reliable method for this analysis, enabling manufacturers to accurately determine protein levels in their products, ensuring adequate amounts of essential nutrients for joint support.

Glucosamine Quantification by HPLC

Glucosamine is essential for building and repairing knee cartilage. Testing glucosamine levels in joint health supplements allows manufacturers to effectively assess product quality and efficacy. HPLC analysis is a crucial tool for evaluating joint health supplement quality. It enables manufacturers to accurately identify the amount of active ingredients in the product, which is vital for improving formulas and developing products with maximum joint support effectiveness. 

Chondroitin Quantification by HPLC

Chondroitin enhances joint flexibility and reduces friction. Testing chondroitin levels in joint health supplements is a vital way to assess product effectiveness in joint support. This test allows manufacturers to confirm that their products contain adequate amounts of essential nutrients for joint health and can optimize product formulas for maximum effectiveness. HPLC analysis of chondroitin helps manufacturers ensure product quality and build consumer trust.

Hyaluronic Acid Quantification by HPLC

Hyaluronic acid is crucial for increasing joint moisture and reducing inflammation. Testing hyaluronic acid levels in joint health supplements allows manufacturers to confirm sufficient amounts for joint nourishment and repair. This test is essential for building confidence in product quality. HPLC analysis of hyaluronic acid helps manufacturers optimize product formulas for maximum joint support effectiveness and ensure product safety before market release. 

Anti-Inflammatory Activity Testing by Nitric Oxide Assay

This test evaluates the effectiveness of joint health supplements in reducing inflammation. It measures Nitric Oxide (NO) levels, a substance involved in inflammatory processes in the body. Anti-inflammatory activity testing by nitric oxide assay is a crucial step in assessing the quality of joint health supplements. 

Immunomodulation Efficacy Testing: IL6 and TNF-alpha

This test assesses the effectiveness of joint health supplements in boosting the immune system. IL-6 (Interleukin-6) is a multifunctional cytokine involved in both promoting and inhibiting inflammation, participating in the immune response to infection and injury. TNF-α is a pro-inflammatory cytokine that plays a role in the immune response to infection and injury but can also cause tissue damage if overproduced. This test focuses on measuring the levels of IL6 and TNF-alpha, substances involved in immune processes in the body. 

Cell Toxicity Testing of Products

This test evaluates the safety of dietary supplements at the cellular level. It helps determine if the product is not toxic to cells, which is essential for assessing product safety. Cell toxicity testing can be done using cell cultures in the laboratory to assess the effects of product ingredients on cells. 

Contact Us for Knee and Joint Health Supplement Product Efficacy Testing Services

VISBIO Co., Ltd. is committed to providing knee and joint health supplement testing services to meet the demands of today’s highly competitive market and increasing consumer expectations. We have developed a comprehensive testing package to ensure that products tested in our laboratory are certified for their true effectiveness. With a team of experts, our company is ready to be a trusted partner in developing and adding value to your products. With this experience and expertise, VISBIO Co., Ltd. aims to help manufacturers and brand owners build brands that are credible and trusted by consumers worldwide.

If you need further advice on knee and joint health supplement product testing services from our experts, please submit your product details for assessment or schedule a meeting with us to discuss suitable testing options for your product. You can reach us through our company’s contact channels [click here].

Literature:

  • Lugo, J. P., Saiyed, Z. M., & Lane, N. E. (2016). Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study. Nutrition journal, 15(1), 14.   
  • Clegg, D. O., Reda, D. J., Harris, C. L., Klein, M. A., O’Dell, J. R., Hooper, M. M., … & Bradley, J. D. (2006). Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis. New England Journal of Medicine, 354(8), 795-808.   
  • Wang, C. T., Lin, J., Chang, C. Y., Lin, Y. T., & Hou, S. M. (2011). Therapeutic effects of hyaluronic acid on osteoarthritis of the knee. A meta-analysis of randomized controlled trials. Journal of bone and joint surgery. American volume, 93(23), 2115-2127.   
  • Daily, J. W., Yang, M., & Park, S. (2016). Efficacy of turmeric extracts and curcumin for alleviating the symptoms of joint arthritis: a systematic review and meta-analysis of randomized clinical trials. Journal of medicinal food, 19(8), 717-729.